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TMS evaluations were performed at baseline (T0), four weeks (T1), and eight weeks (T2). To measure the chronic effects of CE training on CSE measures, TMS was applied at rest at each time point. Acute CSE changes were determined by measuring the difference between pre- and post- a 15-minute HIIT session (post-HIIT–pre-HIIT), with loads individually adjusted based on a previous GXT. CE: cardiovascular exercise, CSE: corticospinal excitability, GXT: graded exercise test, HIIT: high-intensity interval training, TMS: <t>transcranial</t> magne c <t>stimulation.</t>
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TMS evaluations were performed at baseline (T0), four weeks (T1), and eight weeks (T2). To measure the chronic effects of CE training on CSE measures, TMS was applied at rest at each time point. Acute CSE changes were determined by measuring the difference between pre- and post- a 15-minute HIIT session (post-HIIT–pre-HIIT), with loads individually adjusted based on a previous GXT. CE: cardiovascular exercise, CSE: corticospinal excitability, GXT: graded exercise test, HIIT: high-intensity interval training, TMS: transcranial magne c stimulation.

Journal: medRxiv

Article Title: The Effects of Cardiovascular Exercise on Corticospinal Excitability in People with Subacute Stroke

doi: 10.64898/2025.12.02.25341471

Figure Lengend Snippet: TMS evaluations were performed at baseline (T0), four weeks (T1), and eight weeks (T2). To measure the chronic effects of CE training on CSE measures, TMS was applied at rest at each time point. Acute CSE changes were determined by measuring the difference between pre- and post- a 15-minute HIIT session (post-HIIT–pre-HIIT), with loads individually adjusted based on a previous GXT. CE: cardiovascular exercise, CSE: corticospinal excitability, GXT: graded exercise test, HIIT: high-intensity interval training, TMS: transcranial magne c stimulation.

Article Snippet: Transcranial magnetic stimulation offers a highly focused spatial resolution (1-2 cm) for assessing CSE from the CST ( ; ).

Techniques:

Flow chart of the Randomized Controlled Trial. CE: cardiovascular exercise, n: number of participants, TMS: transcranial magnetic stimulation, T0: baseline, T1: four weeks, T2: eight weeks

Journal: medRxiv

Article Title: The Effects of Cardiovascular Exercise on Corticospinal Excitability in People with Subacute Stroke

doi: 10.64898/2025.12.02.25341471

Figure Lengend Snippet: Flow chart of the Randomized Controlled Trial. CE: cardiovascular exercise, n: number of participants, TMS: transcranial magnetic stimulation, T0: baseline, T1: four weeks, T2: eight weeks

Article Snippet: Transcranial magnetic stimulation offers a highly focused spatial resolution (1-2 cm) for assessing CSE from the CST ( ; ).

Techniques: